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pentobarbital will minimize the level or result of piroxicam by influencing hepatic enzyme CYP2C9/10 metabolism. Slight/Importance Unknown.pentobarbital will lower the extent or impact of temsirolimus by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.Keep an eye on Carefully (1)pentobarbital will decrease the extent or